lgca.nove_ib_interactions.go_or_grow_glioblastoma¶

lgca.nove_ib_interactions.go_or_grow_glioblastoma(lgca)¶

Clone-level go-or-grow dynamics for glioblastoma evolution.

Cells switch between migratory and resting phenotypes according to the local neighbourhood density. Resting cells proliferate with a birth rate stored on their family, and driver mutations found new families with increased birth rate and inherited switch sensitivity.