lgca.ib_interactions.go_and_grow_mutations

lgca.ib_interactions.go_and_grow_mutations(lgca)

Birth-death dynamics with explicit family tracking and mutations.

Cells die with probability interaction_params['r_d']. Proliferation rates are either constant or family dependent depending on interaction_params['effect'] ('passenger_mutation' or 'driver_mutation'). With probability interaction_params['r_m'] a dividing cell founds a new family. In the driver case the new family’s r_b is multiplied by interaction_params['fitness_increase'].

Parameters:

lgca (BaseLGCA) – LGCA instance that will be updated.

Notes

The LGCA object and its property lists are modified in place.